The District is one of the oldest in Uganda. Originally, it was called Bunyoro District and in 1974, to become North Bunyoro until 1980 when it became
Hoima District, it has been thus to date. However, in 1991 part of the district was curved out to become Kibaale District. In 2018 stll another part of the district was curved out to become Kikuube District.